Bio Summary

Róisín did a PhD under the joint supervision of Prof. Marina Lynch and Prof. Kingston Mills in Trinity College Dublin, Ireland, studying the effect of infection on the brain with age and in Alzheimer’s disease. Afterwards, she worked as a post doc in the Lynch lab on biomarker development in dementia, before joining Prof. Michael Heneka’s lab at the DZNE in Bonn, Germany. During her post doc with Prof. Heneka, Róisín investigated new roles for the NLRP3 inflammasome in contributing to Alzheimer’s disease, in addition to developing novel methods to inhibit NLRP3 inflammasome activation. Róisín joined Prof. Eicke Latz’s group at the DZNE and the III in 2021, where she was a senior postdoctoral researcher and an Alzheimer Forschung Initiative (AFI) project leader, overseeing a team of scientists together with Prof. Latz. In 2024 Róisín was awarded a Fellowship from the DZNE to establish her own research group. Her work examines how immune signalling influences microglial metabolic reprogramming, and looks to the role of metaflammation in driving neurodegenerative disease

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